About Us
Attivare Therapeutics, founded by a dedicated team from the Wyss Institute at Harvard, is focused on tackling the formidable challenge of treating tumors with low immunogenicity. Our innovative approach centers around the development of the ATTImmune platform. This groundbreaking technology utilizes our proprietary biomaterial scaffold, capable of recruiting, reprogramming, and releasing target immune cells. The ATTImmune scaffold can be customized with various immunomodulators to effectively reprogram the immune environment.
Our platform offers unprecedented 3D spatiotemporal control of bioactive components, significantly enhancing both the magnitude and durability of patient immune responses. Additionally, the ATTImmune platform integrates seamlessly with standard care practices and has potential applications beyond oncology, including the treatment of infectious diseases.
Platform Technology
The ATTImmune platform technology employs a biomaterial scaffold to establish a new physical microenvironment within the body, concentrating and activating immune cells. Simultaneously, it delivers immunomodulatory agents to these resident cells, effectively reprogramming the immune response and overcoming tolerance to cancer antigens.
Pipeline
| Program | Agent | Lead ID | Lead Optimization | IND-enabling |
| Oncology | ||||
| ATT-02 Solid Tumor |
IL-12 | |||
| ATT-01 AML |
GM-CSF, CpG | |||
| Solid Tumor | Stealth | |||
| Infectious Disease | ||||
| ATT-03 Infectious disease |
Stealth | |||
| Vaccine | mRNA, Stealth |
Our Executive Team

David Sherris
President, CEO, Chairman of Board of Directors

Robert Pierce, MD
CMO

Ed Doherty
CTO/Co-Founder

Jess McDonough
COO/Co-Founder

Fernanda Langellotto
Associate Director,
Co-founder

Ben Seiler
Scientist, Co-Founder

David Sherris
Chairman of Board

Jess McDonough
Board Member

Larry Turka
Board Member

Lucy Wang
Board Member

Joaquim Trias
Board Member

George Church

Alejandro Gutierrez

Jacalyn Rosenblatt

Stefan Glück

David Mooney


