We develop cutting-edge immuno-therapeutics with unparalleled efficacy and durability, specifically designed to combat tumors with low immunogenicity.

About Us

Attivare Therapeutics, founded by a dedicated team from the Wyss Institute at Harvard, is focused on tackling the formidable challenge of treating tumors with low immunogenicity. Our innovative approach centers around the development of the ATTImmune platform. This groundbreaking technology utilizes our proprietary biomaterial scaffold, capable of recruiting, reprogramming, and releasing target immune cells. The ATTImmune scaffold can be customized with various immunomodulators to effectively reprogram the immune environment.

Our platform offers unprecedented 3D spatiotemporal control of bioactive components, significantly enhancing both the magnitude and durability of patient immune responses. Additionally, the ATTImmune platform integrates seamlessly with standard care practices and has potential applications beyond oncology, including the treatment of infectious diseases.

Platform Technology

The ATTImmune platform technology employs a biomaterial scaffold to establish a new physical microenvironment within the body, concentrating and activating immune cells. Simultaneously, it delivers immunomodulatory agents to these resident cells, effectively reprogramming the immune response and overcoming tolerance to cancer antigens.

Pipeline

Program Agent Lead ID Lead Optimization IND-enabling
Oncology        
ATT-02
Solid Tumor P
IL-12      
ATT-01
AML P
GM-CSF, CpG      
Solid Tumor  Stealth      
Infectious Disease        
ATT-03
Infectious disease P
Stealth    
Vaccine mRNA, Stealth  

Our Executive Team

David Sherris

President, CEO, Chairman of Board of Directors

Robert Pierce, MD

CMO

Ed Doherty

CTO/Co-Founder

Jess McDonough

COO/Co-Founder

Fernanda Langellotto

Associate Director,
Co-founder

Ben Seiler

Scientist, Co-Founder

David Sherris

Chairman of Board

Jess McDonough

Board Member

Larry Turka

Board Member

Lucy Wang

Board Member

Joaquim Trias

Board Member

George Church

Alejandro Gutierrez

Jacalyn Rosenblatt

Stefan Glück

David Mooney

Paul Ehrlich